Our September 24th’ Bioscience ClubhouseCT was the kick-off of the Fall season. The Study in New Haven provided a very fine venue, with pizza by Aerotek. The atmosphere at this ClubhouseCT felt like our community has joined together to give this event momentum. It was wonderful to feel the enthusiasm and interest in the room as Uday Khire shared his experiences using the platform of synthetic organic chemistry, especially in area of macrocyclics, to build two biotech companies, Cheminpharma, and its spin out Allomek. Clearly Uday is quite a determined entrepreneur, passionate about using chemistry to make new medicines. Carefully leveraging revenue and other resources from his core chemistry services business, Cheminpharma, Uday has produced a biologically and pharmacokinetically sound molecule CIP-137401 ready for later stage preclinical work to ready it for human tests as a cancer therapeutic or interestingly, for treatment of a rare cardiomyopathy. Uday has achieved what is very hard….finding a way to make the resources and priorities within a chemistry service organization support Allomek’s drug discovery chemistry and biology programs. He has worked to access academic collaboration and a wide palette of our State funding sources to bootstrap his endeavors.

Uday shared some of his insights into why CT chemistry service providers well fit into the large worldwide competition of such providers… especially in Asia. He commented on importance of his proximity and time change to partners, his personal network from his time at big pharma, his experience and flexibility and finally, that the price gap between overseas FTE rates compared to those in the US are narrowing.

The business development discussion showed the audience opportunities for collaboration with Allomek and Cheminpharma and touched on Uday’s steps to begin to find a licensing partner as he proceeds through the funding Valley of Death to an IND. There was what appeared to be some good discussion during networking about how different companies could help each other. And by the way, Uday also mentioned that he is looking to hire a Master’s level chemist.

All Clubhousers are clearly committed to growing their piece of CT’s bioscience cluster and finding ways to learn and to work with each other. We appreciate everyone’s ideas and donations to support this grassroot’s forum that builds, educates and connects our community.


By Susan Froshauer
President & CEO, CURE