John G. Houston, Ph.D.
CSO & President of R&D, Arvinas
John G. Houston is currently the CSO and President of R&D at Arvinas and has over 28 years of experience in the pharmaceutical and biotech arena. Prior to this appointment John was Senior Vice President of Specialty Discovery at Bristol-Myers Squibb where he worked for over 18 years in roles of increasing responsibility. He ran all of the disease science biology departments in research such as Oncology, Immuno-Oncology, Immuno-Sciences, Fibrotic Diseases, Genetically Defined Diseases, Neuroscience, Cardiovascular and Virology, as well as accountability for the various technology platform organizations such as Applied Biotechnology, Leads Discovery & Optimization, Genomics, Biologics Discovery California (formerly Medarex) and Zymogenetics in Seattle. For many years he was the global Disease Strategy Team co-chair for Neuroscience and the co-chair for the Neuroscience Early Assets development strategy. He was also the site head at the Wallingford, CT facility and a member of the BMS R&D Executive Committee reporting to the Head of Discovery. He also chaired the Target Portfolio Committee with governance accountability in the early research and development phase of the BMS portfolio.
With his teams and his BMS Research colleagues, he progressed over 180 compounds into early development, several of which have advanced into late stage clinical testing and beyond. He was a member of the BMS senior leadership team that achieved 14 NDA’s over a 10 year period.
John was also the principal architect and driver of the ‘Leveraging Technology’ initiative at BMS which oversaw the design and implementation of an industry leading integrated lead discovery and optimization process. This initiative created revolutionary changes in the discovery process at BMS with significant improvements in capacity, speed and cost control resulting in marked increases in research productivity and success rates.
Prior to joining Bristol-Myers Squibb, Dr. Houston worked at Glaxo Welcome Research and
Development in the UK, where he served as head of the Lead Discovery Unit.
John completed post-doctoral studies with Professor Julia Douglas at Glasgow University,
and obtained his Ph.D. with Professor Brian Catley in Microbial Biochemistry from Heriot-Watt University, Edinburgh.