The cause of ulcerative colitis, a debilitating disease of the intestine, is unclear. A Yale-led study has illuminated the role of a protein that plays a key part in the development of the condition. The research could lead to the development of new therapies to treat the painful disease … more

Congenital heart disease (CHD) is the most common of all birth defects. A massive, multi-institutional project that analyzed all genes from more than 1200 CHD patients and their parents has identified new mutations that contribute to the disease. Results showed that some of the gene mutations linked to severe CHD were also associated with later neurodevelopmental problems such as autism … more